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So, there’s a dark joke about why ECT (Electro Convulsive Therapy) is (mostly temporarily) effective in treatment of depression.
First, you should know, ECT has a strong side effect of amnesia, mostly temporary amnesia.
So, you get ECT, you forget why (you think) your life sucks and your outlook on everything improves, depressive symptoms fade - until your memory comes back.
People in all walks of life get serious depression, including high rates of suicide.